Migraines and Seizures drugs to increase risk of Kidney Stones
By: Russell Smith

Topiramate commonly called topamax, a famous drug used by migraine and seizures patients and highly prescribed to treat these cases have been found to increase the risk of kidney stones. It has been confirmed that the drug increases the propensity of calcium phosphate as per the research undertaken by the UT Southwestern Center.

Numerous reports have described an association between topiramate and the development of kidney stones, but this complication had not been well recognized and physicians have not informed patients about the risk, the UT Southwestern researchers said.

It has been found that a high number of Americans suffer from migraines and women are affected thrice times more often then men. Due to this reason the drug named Topiramate is among the most commonly prescribed and used by the patients.

Researchers found that taking topiramate on a long-term basis, or for about one year, caused systemic metabolic acidosis - a buildup of excessive acid in the blood - as a result of the inability of the kidney to excrete acid. Topiramate use also increased the urine pH and lowered urine citrate, an important inhibitor of kidney-stone formation.

There is a strong need to focus and find a way to the development of kidney stones for the users of this drug. Various studies have been undertaken for the same. And the researchers and doctors are expected to come up with a positive remedy soon.

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